I don't. I just don't. I cannot in anyway understand scientists who are offended that they have to some up with some thin veneer of health-relevance to justify the grant award they are seeking. The H in NIH stands for "Health". The mission statement reads:
NIH’s mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability.
Yeah, sure, if you end at the seventh word, you can convince yourself that the NIH is about basic research. Maybe you get to continue on to the fifteenth. But this is a highly selective reading. I just don't see where it is a burden to think for a minute or two about whether you are doing anything to address the second half of the statement.
After all, you are asking the taxpayers of the US to front you some serious cash. Millions of dollars for many of the PIs who are complaining about how hard it is to get basic research grants funded (BRAINI proponents, I'm looking at you). It really isn't that much of an insult to ask you to pay something back on the matter of public health.