Archive for the 'Science Politics' category

Logothetis driven out of monkey research

May 04 2015 Published by under Animals in Research, Neuroscience, Science Politics

Neuroscientist Nikos Logothetis (PubMed) has informed his colleagues that he is stopping his long running nonhuman primate research program. An article in ScienceInsider by Gretchen Vogel details the issues:

Nikos Logothetis, a director at the Max Planck Institute for Biological Cybernetics in Tübingen, Germany, says he will conclude his current experiments on macaques “as quickly as possible” and then shift his research to rodent neural networks. In a letter last week to fellow primate researchers, Logothetis cites a lack of support from colleagues and the wider scientific community as key factors in his decision.

This is not the "start" as was alleged by a Twitter person today. This is a long running trend that has been going on for decades. Productive laboratories that use nonhuman primates have been closing one by one. The decision by Harvard to shutter the New England National Primate Research Center was shocking in the way it violated the trend for picking off research labs one by one, but it was otherwise simply part of a larger trend.

And why are Universities and Research Institutes like Max Planck divesting themselves of monkey labs as quickly as possible? The Vogel article suggests an answer.

Logothetis’s research on the neural mechanisms of perception and object recognition has used rhesus macaques with electrode probes implanted in their brains. The work was the subject of a broadcast on German national television in September that showed footage filmed by an undercover animal rights activist working at the institute. The video purported to show animals being mistreated.

Logothetis has said the footage is inaccurate, presenting a rare emergency situation following surgery as typical and showing stress behaviors deliberately prompted by the undercover caregiver. ... The broadcast triggered protests, however, and it prompted several investigations of animal care practices at the institute. Investigations by the Max Planck Society and animal protection authorities in the state of Baden-Württemberg found no serious violations of animal care rules.

Emphasis added. This is a typical scenario. In essence, animal rights terrorist fanatics are able to get Universities and Research Institutions to turn their backs on productive researchers simply because they don't want to deal with the headaches any longer. Or because they fear bad press. The accusations are almost always falsified. Baseless. But it doesn't matter. The Universities are running in absolute terror of the fanatics.

Of course it goes beyond that, which is why Logothetis called out his fellow scientists.

The [Max Planck] society is “one of the best scientific organizations worldwide,” Logothetis wrote, but it has failed to take concrete steps against the activists. “I am no longer willing or able to accept the never-ending stream of abuse from animal activists toward myself and my co-workers while seeing them encouraged to increase their aggressive activities by the tolerance and very slow reactions of scientific organizations. There is a clear lack of consequences for illegal actions such as infiltration, violation of privacy, theft of documents, and even intentionally caused distress to animals in order to film supposed animal torture or abnormal behavior,” the letter states.

Logothetis’s letter also faults his scientific colleagues in Tübingen for distancing themselves from the controversy. The neighboring Max Planck Institute for Developmental Biology posted a disclaimer on its website emphasizing that there are no monkeys at the institute, he notes, and colleagues at the nearby Hertie Institute for Clinical Brain Research refused to issue a declaration of support.

Pastor Niemöller once observed:

First they came for the Socialists, and I did not speak out—
Because I was not a Socialist.

Then they came for the Trade Unionists, and I did not speak out—
Because I was not a Trade Unionist.

Then they came for the Jews, and I did not speak out—
Because I was not a Jew.

Then they came for me—and there was no one left to speak for me.

There are certainly parallels. Biological scientists express a range of attitudes about many things and the use of animals in research is one of them. From fears of coming under assault themselves if they speak up, to discomfort with making an informed decision about the allegations against Professor Logothetis to frank antipathy to research in monkeys, we span the same range as many lay people.

We are easily able to delude ourselves that if we just let the most-detested targets of the terrorists get thrown under the bus, we can live our own lives in relative safety for another few years. Maybe run out the clock on our career before things get too bad.

Money is tight, after all, and gee, well lets not do anything to rile up the nice little old ladies who are poised to donate a few million to the University, eh? Let's not do anything to draw the attention of animal right's Congress Critters. That might make things awkward for the NIH.

Normally this is the point of my post where I exhort you to fight. To stand up and oppose this assault on scientific research. Where I point out to you that after the monkeys (and cats and dogs) comes the goats and the rabbits from which you get your antibodies. Where I tell you that all this pressure is doing is to move certain kinds of research to non-Western countries in which the animal research protections are, at best, at the lever of the US in 1950.

This is the point where I am supposed to be telling you to call your Congress Critter.

But I can't.

Logothetis is not the first and he will not be the last.

We have had ample opportunity for biological scientists to see and be motivated to do something about this situation.

They have not done so.

So I would be wasting my breath.

43 responses so far

I really need to start one of these citation cartels....

From Odyssey:

It's become apparent to me that there is a group of reviewers who all display the same phenotype when it comes to their reviews. They all i) are quick to agree to review manuscripts in our common sub-sub-field, ii) submit their reviews on time, and iii) will recommend acceptance or minor revisions for all manuscripts. All.


On time? Suspicious that.

Did I mention that this bloc of reviewers are all strongly linked to one particular well-known member of our sub-sub-field? Former trainees, co-authors etc.






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NIH's rapid growth has let in a bunch of riff-raff!

I am sure Dr. McKnight realizes that when he asserts that "Biomedical research in the 1960s and 1970s was a spartan game" and "Biomedical research is a huge enterprise now; it attracts riff-raff who never would have survived as scientists in the 1960s and 1970s" he is in fact lauding the very scientists "When I joined the molecular cytology study section in the 1980s.. all kinds of superb scientists" who were the riff-raff the prior generation complained about.

From a very prestigious general Science journal in 1962:

Some of [this change] arises from expressions of concern within the scientific community itself over whether the NIH's rapid growth has sacrificed quality to achieve quantity.

The astute reader will also pick up on another familiar theme we are currently discussing.

And some of it reflects nothing more than the know-nothing ramblings of scientific illiterates, who conclude that if the title of a research project is not readily comprehensible to them, some effort to swindle the government must be involved.

1962, people. 1962.
Greenberg DS. NIH Grants: Policies Revised, but Critics Not Likely To Turn Away. Science. 1962 Dec 28;138(3548):1379-80.

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Congress is dissatisfied with NIH's spending priorities!

This passage appeared in a highly prestigious journal of science.

"Important elements in both Senate and the House are showing increasing dissatisfaction over Congress's decade-long honeymoon with medical research....critics are dissatisfied...with the NIH's procedures for supervising the use of money by its research grantees....NIH officials..argued, rather, that the most productive method in financing research is to pick good people with good projects and let them carry out their work without encumbering them...its growth has been phenomenal....[NIH director}: nor do we believe that most scientific groups in the country have an asking and a selling price for their product which is research activity...we get a realistic appraisal of what they need to do the job..the supervisory function properly belongs to the universities and other institutions where the research takes place....closing remarks of the report are:...Congress has been overzealous in appropriating money for health research".

Continue Reading »

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Thought on the public funding of science

Simple truth of the recentEbola hysteria and the ensuing media coverage of scientists working on hemorrhagic viruses. Approximately 85% of bioscience now wishing ill on a whole lot of people so as to draw attention to their scientific domain.

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Medical marijuana "researcher" fired by U of A

Jul 02 2014 Published by under Cannabis, Public Health, Science Politics

From the LA Times:

The University of Arizona has abruptly fired a prominent marijuana researcher who only months ago received rare approval from federal drug officials to study the effects of pot on patients suffering from post traumatic stress disorder.

The firing of Suzanne A. Sisley, a clinical assistant professor of psychiatry, puts her research in jeopardy and has sparked indignation from medical marijuana advocates.

I bet. Interestingly I see no evidence on PubMed that this Sisley person has any expertise in conducting research at all. I'm not saying I need exhaustive credentials but I'd like to see a published study or two.

Cue the usual raving about how this is all a vast right wing conspiracy to keep down miraculous medication...

Sisley charges she was fired after her research – and her personal political crusading – created unwanted attention for the university from legislative Republicans who control its purse strings.

“This is a clear political retaliation for the advocacy and education I have been providing the public and lawmakers,” Sisley said. “I pulled all my evaluations and this is not about my job performance.”

Well, this IS Arizona we're talking about. I'm going to want to see more* but I guess I am going to have to score myself as sympathetic to the notion that this was a political squelching.
Still, the University is denying the charge...

University officials declined to explain why Sisley’s contract was not renewed, but objected to her characterization.

“The university has received no political pressure to terminate any employee,” said Chris Sigurdson, a university spokesman. He said the university embraces research of medical marijuana, noting that it supported a legislative measure in 2013 permitting such studies to be done on state campuses.

Ok, "embraces", eh? We'll see if that turns out to be true.

h/t: clbs

*if this holds true to form the University will be compelled to make a case for how she wasn't competent at the "clinical assistant professor" category of association with U of A.

4 responses so far

UCLA scientists have been under attack for over a decade

A new post at Speaking for Research details the history:

Back in 2003, Neurobiology Professors John and Madeleine Schlag saw their property vandalized at a home demonstration. “The way it proceeded … we felt that the door was going to be kicked in,” they commented in an interview.

In 2006, Professor Lynn Fairbanks was targeted with an incendiary device. It turned out animal extremists got the wrong address and planted the firebomb at the doorstep of an elderly neighbor.

In June 2007 another firebomb was placed under the vehicle of Professor Arthur Rosenbaum, who dedicated his life to pediatric ophthalmology by helping children with strabismus. His wife later received a threatening note which told her to persuade her husband to stop his research or “…we will do exactly what he does to monkeys to you.”

In 2007, Professor Edythe London finds her home flooded by animal rights extremists, and received the threat, “water was our second choice, fire was our first.”  She decided to reply by explaining, in a thoughtful OpEd in the LA Times, the reasons for her work.

In 2008, the UCLA community saw once again an incendiary device char the front door of a home owned by a Professor, the vandalism of three vehicles parked outside the home of a postdoctoral student, and the firebombing of a university commuter van.

Then, in 2009, the car of Professor David Jentsch, parked in his driveway, is set on fire while he was sleeping at home.  He subsequently received a letter containing razor blades and a threatening note that fantasized about sneaking up behind him and cutting his throat

The harassment of UCLA scientists in their homes has continued on a monthly basis every since. This year, the scientists have decided to organize counter protests.

The next counterdemonstration will be February 15, 2014. If you are local these scientists would appreciate your support.


Please join us to defend UCLA, our science, and the hope for medical advances and new cures.

When: February 15, 10:15am sharp!
Where: NE Corner of Westwood and LeConte

Join us to end the decade-long age of terror at UCLA!

7 responses so far

Dolphins ain't all that either.

Aug 23 2013 Published by under Animals in Research, Psychology, Science Politics

There's a great review of a new book (Are Dolphins Really Smart?,  by Justin Gregg) penned by Jessa Gamble at LWON. Go read because it is incredibly important to realize:

A disproportionate amount of dolphin research time has been devoted to teasing out any potential for language – the science-fictional myth of dolphinese – from their vocalizations. If dolphins had language, we would almost certainly have found it by now. When their vocalizations turned out to be rote and inflexible, “I’m scared!” “I’m mating!” “I see food!” pretty much covers it, the research turned to echolocation clicks. Perhaps dolphins were sending each other 3D holographic messages encoded in their clicks. Nope.


[waccaloon terrorist AR org]’s lawsuit against SeaWorld challenges dolphin captivity under anti-slavery legislation, citing exceptional intelligence as evidence of their “non-human personhood.” When advocacy for the ethical treatment of animals is based on exaggerated claims of their intelligence, it fails to recognize the inherent worth of animals regardless of their similarity to humans. And in dolphins, that similarity is easily refuted. It’s time relieve the dolphins of all our human baggage and realize that evolution has produced all kinds of intelligence, and it’s all around us.

Gamble notes that the book by Gregg systematically dismantles many popular myths about dolphins and, of course, points out that dolphins are total dicks

Adult male dolphins routinely kill porpoises, not for food — or even out of competition for food – but because the porpoise is similar in size to a dolphin calf. The killings serve as practice for their regular infanticidal behaviour, a sure way to ready mothers for mating.

Sounds like a good read.




Repost: Insightful Animal Behavior: A "Sufficiently Advanced Technology"

Jane Goodall, Plagiarist


8 responses so far

Why aren't they citing my papers?

As the Impact Factor discussion has been percolating along (Stephen Curry, Björn Brembs, YHN) it has touched briefly on the core valuation of a scientific paper: Citations!

Coincidentally, a couple of twitter remarks today also reinforced the idea that what we are all really after is other people who cite our work.

More people should cite my papers.

I totally agree. More people should cite my papers. Often.


was a bit discouraged when a few papers were pub'ed recently that conceivably could have cited mine

Yep. I've had that feeling on occasion and it stings. Especially early in the career when you have relatively few publications to your name, it can feel like you haven't really arrived yet until people are citing your work.

Before we get too far into this discussion, let us all pause and remember that all of the specifics of citation numbers, citation speed and citation practices are going to be very subfield dependent. Sometimes our best discussions are enhanced by dissecting these differences but let's try not to act like nobody recognizes this, even though I'm going to do so for the balance of the post....

So, why might you not be getting cited and what can you do about it? (in no particular order)

1) Time. I dealt with this in a prior post on gaming the impact factor by having a lengthy pre-publication queue. The fact of the matter is that it takes a long time for a study that is primarily motivated by your paper to reach publication. As in, several years of time. So be patient.

2) Time (b). As pointed out by Odyssey, sometimes a paper that just appeared reached final draft status 1, 2 or more years ago and the authors have been fighting the publication process ever since. Sure, occasionally they'll slip in a few new references when revising for yet the umpteenth time but this is limited.

3) Your paper doesn't hit the sweet spot. Speaking for myself, my citation practices lean this way for any given point I'm trying to make. The first, best and most recent. Rationale's vary and I would assume most of us can agree that the best, most comprehensive, most elegant and all around most scientifically awesome study is the primary citation. Opinions might vary on primacy but there is a profound sub-current that we must respect the first person to publish something. The most-recent is a nebulous concept because it is a moving target and might have little to do with scientific quality. But all else equal, the more recent citations should give the reader access to the front of the citation thread for the whole body of work. These three concerns are not etched in stone but they inform my citation practices substantially.

4) Journal identity. I don't need to belabor this but suffice it to say some people cite based on the journal identity. This includes Impact Factor, citing papers on the journal to which one is submitting, citing journals thought important to the field, etc. If you didn't happen to publish there but someone else did, you might be passed over.

5) Your paper actually sucks. Look, if you continually fail to get cited when you think you should have been mentioned, maybe your paper(s) just sucks. It is worth considering this. Not to contribute to Imposter Syndrome but if the field is telling you to up your game...up your game.

6) The other authors think your paper sucks (but it doesn't). Water off a duck's back, my friends. We all have our opinions about what makes for a good paper. What is interesting and what is not. That's just the way it goes sometimes. Keep publishing.

7) Nobody knows you, your lab, etc. I know I talk about how anyone can find any paper in PubMed but we all need to remember this is a social business. Scientists cite people they know well, people they've just been chatting with at a poster session and people who have just visited for Departmental seminar. Your work is going to be cited more by people for whom you/it/your lab are most salient. Obviously, you can do something about this factor...get more visible!

8) Shenanigans (a): Sometimes the findings in your paper are, shall we say, inconvenient to the story the authors wish to tell about their data. Either they find it hard to fit it in (even though it is obvious to you) or they realize it compromises the story they wish to advance. Obviously this spans the spectrum from essentially benign to active misrepresentation. Can you really tell which it is? Worth getting angsty about? Rarely.....

9) Shenanigans (b): Sometimes people are motivated to screw you or your lab in some way. They may feel in competition with you and, nothing personal but they don't want to extend any more credit to you than they have to. It happens, it is real. If you cite someone, then the person reading your paper might cite them. If you don't, hey, maybe that person will miss it. Over time, this all contributes to reputation. Other times, you may be on the butt end of disagreements that took place years before. Maybe two people trained in a lab together 30 years ago and still hate each other. Maybe someone scooped someone back in the 80s. Maybe they perceived that a recent paper from your laboratory should have cited them and this is payback time.

10) Nobody knows you, your lab, etc II, electric boogaloo. Cite your own papers. Liberally. The natural way papers come to the attention of the right people is by pulling the threads. Read one paper and then collect all the cited works of interest. Read them and collect the works cited in that paper. Repeat. This is the essence of graduate school if you ask me. And it is a staple behavior of any decent scientist. You pull the threads. So consequently, you need to include all the thread-ends in as many of your own papers as possible. If you don't, why should anyone else? Who else is most motivated to cite your work? Who is most likely to be working on related studies? And if you can't find a place for a citation....

16 responses so far

Date these comments!

from a prestigious general science journal:

"Important elements in both Senate and the House are showing increasing dissatisfaction over Congress's decade-long honeymoon with medical research....critics are dissatisfied...with the NIH's procedures for supervising the use of money by its research grantees....NIH officials..argued, rather, that the most productive method in financing research is to pick good people with good projects and let them carry out their work without encumbering them...its growth has been phenomenal....[NIH director}: nor do we believe that most scientific groups in the country have an asking and a selling price for their product which is research activity...we get a realistic appraisal of what they need to do the job..the supervisory function properly belongs to the universities and other institutions where the research takes place....closing remarks of the report are:...Congress has been overzealous in appropriating money for health research".

Okay, people, ballpark the date this was published!

5 responses so far

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