I am sure Dr. McKnight realizes that when he asserts that "Biomedical research in the 1960s and 1970s was a spartan game" and "Biomedical research is a huge enterprise now; it attracts riff-raff who never would have survived as scientists in the 1960s and 1970s" he is in fact lauding the very scientists "When I joined the molecular cytology study section in the 1980s.. all kinds of superb scientists" who were the riff-raff the prior generation complained about.
From a very prestigious general Science journal in 1962:
Some of [this change] arises from expressions of concern within the scientific community itself over whether the NIH's rapid growth has sacrificed quality to achieve quantity.
And some of it reflects nothing more than the know-nothing ramblings of scientific illiterates, who conclude that if the title of a research project is not readily comprehensible to them, some effort to swindle the government must be involved.
1962, people. 1962.
Greenberg DS. NIH Grants: Policies Revised, but Critics Not Likely To Turn Away. Science. 1962 Dec 28;138(3548):1379-80.