I've been reading a little chatter from a few newish looking PI types today on the perennial topic of lab size. It provides a nice counter to a recent post at the Sb DM and a note today from Mike the Mad Biologist.
The most defined statement was to the effect that "we can all agree" that 4 R01 awards (concurrently) is excessive. The corollary is that science would be so much more efficient and productive if individual PIs were capped somewhere south of 4 R01s.
I'll let the comments run for a bit but I have some woodshed time for the n00b PIs saved up for later.