From today's Cell:
We realized that the anti-IKKa (IB) loading controls presented in Figures 3A, 3B, 3C, and 4C are duplicate presentations of the same gel lanes and do not represent the correct controls for the individual experiments. In addition, the anti-IKKa (IB) loading control in the right panel of Figure 4C is an inadvertent duplication of the DNA-PKcs (IB) data in the left panel of Figure 5F. These errors in figure preparation limit the interpretability of the related experimental data in these figures, which are an essential component of the support for the main conclusions of the paper regarding the activation of IKK and NF-kB. We are therefore retracting this paper. We apologize for these errors and for any inconvenience they may have caused. Despite these errors, we stand by the reproducibility of the experimental data and the conclusion, which has been reached by numerous subsequent studies, that IKK and NF-kB are required for activation of innate immunity.
Augusto Lois, a coauthor on the original manuscript, was not reachable via any of the available contact information and therefore has not seen or agreed to the text of this Retraction.
Realized!? Inadvertent!? Limit the interpretability!?